BD-PB0814-APCS Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

APCS Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB0814

产品名称

APCS Rabbit Polyclonal Antibody (C-term)

别名

Serum amyloid P-component, SAP, 95S alpha-1-glycoprotein, Serum amyloid P-component(1-203), APCS, PTX2

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001630.1

Human Swissprot No.

P02743

特异性

This APCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

25kDa

同种型

Rabbit Ig

背景介绍

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

组织表达

Found in serum and urine.

细胞定位

Secreted.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

APCS Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APCS antibody detected the APCS protein (arrow).

APCS antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.