产品名称
PDE7B Rabbit Polyclonal Antibody (C-term)
别名
cAMP-specific 3',5'-cyclic phosphodiesterase 7B, PDE7B
Human Gene ID
NP_061818.1
Human Swissprot No.
Q9NP56
特异性
This PDE7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human PDE7B.
背景介绍
The 3',5'-cyclic nucleotides cAMP and cGMP function as
second messengers in a wide variety of signal transduction
pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs)
catalyze the hydrolysis of cAMP and cGMP to the corresponding
5'-monophosphates and provide a mechanism to downregulate cAMP and
cGMP signaling. This gene encodes a cAMP-specific
phosphodiesterase, a member of the cyclic nucleotide
phosphodiesterase family.
组织表达
Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
