产品名称
IGSF5 Rabbit Polyclonal Antibody (N-term)
别名
Immunoglobulin superfamily member 5, IgSF5, Junctional adhesion molecule 4, JAM-4, IGSF5, JAM4
Human Gene ID
NP_001073913.1
Human Swissprot No.
Q9NSI5
特异性
This IGSF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human IGSF5.
背景介绍
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity).
细胞定位
Apical cell membrane {ECO:0000250|UniProtKB:Q5VJ70}; Single-pass type I membrane protein. Cell junction, tight junction {ECO:0000250|UniProtKB:Q5VJ70}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
