产品名称
ITBP2 Rabbit Polyclonal Antibody
蛋白名称
Integrin beta-1-binding protein 2 (Melusin)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UKP3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UKP3/entry
Mouse Swissprot No.
Q9R000
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R000
免疫原
Synthesized peptide derived from human protein . at AA range: 10-90
特异性
ITBP2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein.,function:May play a role during maturation and/or organization of muscles cells.,similarity:Contains 1 CS domain.,similarity:Contains 2 CHORD domains.,subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium.,tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues.,
组织表达
Expressed in skeletal and cardiac muscles but not in other tissues.
功能
domain:The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca(2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein.,function:May play a role during maturation and/or organization of muscles cells.,similarity:Contains 1 CS domain.,similarity:Contains 2 CHORD domains.,subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium.,tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
