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MYCT1 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB0789
产品名称
MYCT1 Rabbit Polyclonal Antibody (C-term)
别名
Myc target protein 1, Myc target in myeloid cells protein 1, MYCT1, MTLC, MTMC1
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_079383.2
Human Swissprot No.
Q8N699
特异性
This MYCT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the C-terminal region of human MYCT1.
稀释度
WB~~1:1000;FC~~1:10~50
预测分子量
27kDa
同种型
Rabbit Ig
背景介绍
May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known phenotypic features associated with MYC, including promotion of apoptosis, alteration of morphology, enhancement of anchorage-independent growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation (By similarity).
组织表达
Down-regulated in gastric cancer tissues.
细胞定位
Nucleus. Note=Expressed in nuclei of hepatocellular carcinoma cell line BEL-7402 cells
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

MYCT1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the MYCT1 antibody detected the MYCT1 protein (arrow).

MYCT1 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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