BD-PB0787-CASC4 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

CASC4 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB0787

产品名称

CASC4 Rabbit Polyclonal Antibody (C-term)

别名

Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_612432.2;NP_816929.1

Human Swissprot No.

Q6P4E1

特异性

This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.

稀释度

WB~~1:1000;FC~~1:10~50

预测分子量

49kDa

同种型

Rabbit Ig

背景介绍

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.

细胞定位

Membrane; Single-pass type II membrane protein

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

CASC4 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CASC4 antibody detected the CASC4 protein (arrow).

CASC4 Antibody (C-term) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.