BD-PB0786-MCAF2 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

MCAF2 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB0786

产品名称

MCAF2 Rabbit Polyclonal Antibody (Center)

别名

Activating transcription factor 7-interacting protein 2, ATF7-interacting protein 2, MBD1-containing chromatin-associated factor 2, ATF7IP2, MCAF2

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Gene ID

NP_001243089.1;NP_079273.2

Human Swissprot No.

Q5U623

特异性

This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human MCAF2.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

76kDa

同种型

Rabbit Ig

背景介绍

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).

细胞定位

Nucleus.

期货

现货

纯化

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

MCAF2 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the MCAF2 antibody detected the MCAF2 protein (arrow).

MCAF2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MCAF2 antibody detected the MCAF2 protein (arrow).

MCAF2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCAF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

MCAF2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.