产品名称
LHFPL5 Rabbit Polyclonal Antibody (C-term)
别名
Tetraspan membrane protein of hair cell stereocilia, Lipoma HMGIC fusion partner-like 5 protein, LHFPL5, TMHS
Human Gene ID
NP_872354.1
Human Swissprot No.
Q8TAF8
特异性
This LHFPL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the C-terminal region of human LHFPL5.
背景介绍
This gene is a member of the lipoma HMGIC fusion partner
(LHFP) gene family, which is a subset of the superfamily of
tetraspan transmembrane protein encoding genes. Mutations in this
gene result in deafness in humans, and a mutation in a similar gene
in mice results in deafness and vestibular dysfunction with severe
degeneration of the organ of Corti. It is proposed to function in
hair bundle morphogenesis.
细胞定位
Cell membrane {ECO:0000250|UniProtKB:Q4KL25}; Multi-pass membrane protein. Note=Efficient localization to the plasma membrane requires the presence of PCDH15 {ECO:0000250|UniProtKB:Q4KL25}
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
