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FBXO2 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB0748
产品名称
FBXO2 Rabbit Polyclonal Antibody (C-term)
别名
F-box only protein 2, FBXO2, FBX2
类别
常规抗体
推荐应用
WB
反应种属
Human, Mouse
Human Gene ID
NP_036300.2
Human Swissprot No.
Q9UK22
特异性
This FBXO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 244-271 amino acids from the C-terminal region of human FBXO2.
稀释度
FC~~1:10~50;WB~~1:1000
预测分子量
33kDa
同种型
Rabbit Ig
背景介绍
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state.
细胞定位
Cytoplasm. Microsome membrane; Peripheral membrane protein; Cytoplasmic side
期货
现货
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

FBXO2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

FBXO2 Antibody (C-term) western blot analysis in mouse brain tissue and HepG2,293 cell line lysates (35ug/lane).This demonstrates the FBXO2 antibody detected the FBXO2 protein (arrow).

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