产品名称
ILRL2 Rabbit Polyclonal Antibody
蛋白名称
Interleukin-1 receptor-like 2 (Interleukin-1 receptor-related protein 2) (IL-1Rrp2) (IL1R-rp2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9HB29
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HB29/entry
Mouse Swissprot No.
Q9ERS7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ERS7
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q62929
免疫原
Synthesized peptide derived from human protein . at AA range: 330-410
特异性
ILRL2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008],
组织表达
Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level.
细胞定位
Membrane; Single-pass type I membrane protein .
功能
function:Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B.,miscellaneous:Does not bind interleukin 1 alpha (IL-1A) or interleukin 1 beta (IL-1B).,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 TIR domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
