BD-PB0706

HNMT(10A14)Mouse Monoclonal Antibody

Histamine N-methyltransferase, HMT, HNMT

常规抗体

WB

Human

NP_001019245.1;NP_001019246.1;NP_008826.1

P50135

Purified His-tagged HNMT protein(Fragment) was used to produced this monoclonal antibody.

WB~~1:100~1000

33kDa

IgG1

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Cytoplasm.

现货

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.