BD-PB0697

PDK4(7L6)Mouse Monoclonal Antibody

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4, PDK4, PDHK4

常规抗体

WB

Human, Rat, Mouse

NP_002603.1

Q16654

Purified His-tagged PDK4 protein(Fragment) was used to produced this monoclonal antibody.

WB~~1:1000

46kDa

IgG1

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Ubiquitous; highest levels of expression in heart and skeletal muscle.

Mitochondrion matrix.

现货

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.