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PAX6 (17Y4)Mouse Monoclonal Antibody(Ascites)

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产品基本信息

产品货号
BD-PB0691
产品名称
PAX6 (17Y4)Mouse Monoclonal Antibody(Ascites)
别名
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_000271.1;NP_001121084.1;NP_001245393.1;NP_001245394.1;NP_001595.2
Human Swissprot No.
P26367
特异性
This PAX6 Monoclonal antibody was raised using purified His-tagged recombinant human PAX6.
稀释度
WB~~1:500~16000;IF~~1:10~50
预测分子量
47kDa
同种型
IgM,K
背景介绍
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].
组织表达
[Isoform 1]: Expressed in lymphoblasts.
细胞定位
Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016}
期货
现货
纯化
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

PAX6 western blot analysis in 293 cell line lysates (35μg/lane).This demonstrates the PAX6 antibody detected the PAX6 protein (arrow).

Confocal immunofluorescent analysis of PAX6 Antibody (Ascites) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-mouse lgG (green). Actin filaments have been labeled with Alexa Fluor® 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).

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