产品名称
IFNK Rabbit Polyclonal Antibody
基因名称
IFNK UNQ6124/PRO20084
蛋白名称
Interferon kappa (IFN-kappa)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9P0W0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9P0W0/entry
Mouse Swissprot No.
Q7TSL0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TSL0
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
IFNK Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. [provided by RefSeq, Jul 2008],
组织表达
Expressed in keratinocytes, monocytes and in resting dendritic cells.
信号通路
Cytokine-cytokine receptor interaction;RIG-I-like receptor;Jak_STAT;
功能
function:May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.,induction:By viral infection, upon exposure to double-stranded RNA, or upon treatment with either interferon-gamma or interferon-beta.,similarity:Belongs to the alpha/beta interferon family.,tissue specificity:Expressed in keratinocytes, monocytes and in resting dendritic cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
