产品名称
TRAPPC2 Rabbit Polyclonal Antibody (N-term)
别名
Trafficking protein particle complex subunit 2, Sedlin, TRAPPC2, SEDL
Human Gene ID
NP_001011658.1;NP_001122307.2;NP_055378.1
Human Swissprot No.
P0DI81
特异性
This TRAPPC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human TRAPPC2.
背景介绍
TRAPPC2 is thought to be part of
a large multi-subunit complex involved in the targeting and fusion
of endoplasmic reticulum-to-Golgi transport vesicles with their
acceptor compartment. In addition, the encoded protein can bind
c-myc promoter-binding protein 1 and block its transcriptional
repression capability. Mutations in this gene are a cause of
spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene
of this gene is located on chromosome 19, and other pseudogenes are
found on chromosomes 8 and Y.
组织表达
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, placenta and lymphocytes.
细胞定位
Cytoplasm, perinuclear region. Endoplasmic reticulum-Golgi intermediate compartment. Nucleus. Cytoplasm. Note=Localized in perinuclear granular structures.
纯化
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
