BD-PP1477

SAMHD1 (phospho-Thr592) Rabbit Polyclonal Antibody

SAM domain and HD domain-containing protein 1 (EC 3.1.4.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)

常规抗体

SAMHD1 MOP5

SAMHD1 (Thr592)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

25939

https://www.uniprot.org/uniprot/25939

Q9Y3Z3

https://www.uniprot.org/uniprotkb/Q9Y3Z3/entry

56045

https://www.uniprot.org/uniprot/56045

Q60710

https://www.uniprot.org/uniprotkb/Q60710

Synthesized phosho peptide around human SAMHD1 (Thr592)

This antibody detects endogenous levels of Human Mouse Rat SAMHD1 (phospho-Thr592)

WB 1:1000-2000

72kD

-20°C/1 year

Polyclonal, Rabbit,IgG

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1(SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],

Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes (PubMed:11064105). No expression is seen in brain and thymus (PubMed:11064105).

Nucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. .

function:May play a role in mediating proinflammatory responses to TNF-alpha signaling.,induction:By interferon gamma. Up-regulated in TNF-alpha treated lung fibroblasts.,similarity:Contains 1 HD domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,tissue specificity:Expressed in heart, skeletal muscle, spleen, liver, small intestine, placenta, lung and peripheral blood leukocytes. No expression is seen in brain and thymus.,

现货

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.