Cn|En

现货抗体产品库

RPA32/RPA2 (phospho-Ser8) Rabbit Polyclonal Antibody

产品详情 相关文献 产品问答 相关产品

产品基本信息

产品货号
BD-PP1470
产品名称
RPA32/RPA2 (phospho-Ser8) Rabbit Polyclonal Antibody
别名
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
类别
常规抗体
基因名称
RPA2 REPA2 RPA32 RPA34
蛋白名称
RPA32/RPA2 (Ser8)
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
6118
Human Gene Link
https://www.uniprot.org/uniprot/6118
Human Swissprot No.
P15927
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P15927/entry
Mouse Swissprot No.
Q62193
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q62193
Rat Gene ID
59102
Rat Gene Link
https://www.uniprot.org/uniprot/59102
Rat Swissprot No.
Q63528
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q63528
免疫原
Synthesized phosho peptide around human RPA32 and RPA2 (Ser8)
特异性
This antibody detects endogenous levels of Human RPA32 or RPA2 (phospho-Ser8)
稀释度
WB 1:1000-2000
预测分子量
32kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
组织表达
Kidney,Lung,Muscle,
细胞定位
Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .
信号通路
DNA replication;Nucleotide excision repair;Mismatch repair;Homologous recombination;
功能
function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
期货
现货
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

相关文献

产品问答

相关产品

免责声明| 法律支持| 联系方式

市场:027-65023363   行政/人事:027-62439686   邮箱:marketing@brainvta.com  

销售总监:张经理  18995532642  华东区:陈经理 18013970337   华南区:王经理 13100653525   华中/西区:杨经理 18186518905   华北区:张经理 18893721749

地址:中国武汉东湖高新区光谷七路128号中科开物产业园1号楼

Copyright © 武汉枢密脑科学技术有限公司. All RIGHTS RESERVED.
鄂ICP备2021009124号 DIGITAL BY VTHINK