产品名称
MOB1 (phospho-Thr12) Rabbit Polyclonal Antibody
别名
MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55233
Human Swissprot No.
Q9H8S9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H8S9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/232157
Mouse Swissprot No.
Q921Y0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q921Y0
Rat Gene Link
https://www.uniprot.org/uniprot/297387
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q3T1J9
免疫原
Synthesized phosho peptide around human MOB1 (Thr12)
特异性
This antibody detects endogenous levels of Human Mouse Rat MOB1 (phospho-Thr12)
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
组织表达
Adrenal gland, bone marrow, brain, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, heart, spinal cord, fetal brain and fetal liver.
细胞定位
cytosol,extracellular exosome,
功能
function:Stimulates the kinase activity of STK38 and STK38L.,PTM:Phosphorylated.,similarity:Belongs to the MOB1/phocein family.,subunit:Binds STK38 and STK38L.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
