产品名称
HSP72 Rabbit Polyclonal Antibody
蛋白名称
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P54652
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P54652/entry
Mouse Swissprot No.
P17156
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P17156
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P14659
免疫原
Synthesized peptide derived from human protein . at AA range: 470-550
特异性
HSP72 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with ZNF541.,
细胞定位
Cytoplasm, cytoskeleton, spindle . Colocalizes with SHCBP1L at spindle during the meiosis process. .
信号通路
Spliceosome;MAPK_ERK_Growth;MAPK_G_Protein;Endocytosis;Antigen processing and presentation;
功能
function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with ZNF541.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.