产品名称
GPDA Rabbit Polyclonal Antibody
蛋白名称
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P21695
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P21695/entry
Mouse Swissprot No.
P13707
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P13707
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941O35077
免疫原
Synthesized peptide derived from human protein . at AA range: 210-290
特异性
GPDA Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],
组织表达
Expressed in liver (at protein level).
信号通路
Glycerophospholipid metabolism;
功能
catalytic activity:sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH.,enzyme regulation:Inhibited by zinc ions and sulfate.,similarity:Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.