产品名称
HSP90α (phospho-Thr5/7) Rabbit Polyclonal Antibody
别名
Heat shock protein HSP 90-alpha (Heat shock 86 kDa) (HSP 86) (HSP86) (Renal carcinoma antigen NY-REN-38)
基因名称
HSP90AA1 HSP90A HSPC1 HSPCA
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3320
Human Swissprot No.
P07900
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P07900/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/15519
Mouse Swissprot No.
P07901
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P07901
Rat Gene Link
https://www.uniprot.org/uniprot/299331
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P82995
免疫原
Synthesized phosho peptide around human HSP90α (Thr5 and 7)
特异性
This antibody detects endogenous levels of Human Mouse Rat HSP90α (phospho-Thr5 or 7)
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
组织表达
Adult brain,Brain,Brain cortex,Breast,Cajal-Retzius
细胞定位
Nucleus . Cytoplasm . Melanosome . Cell membrane . Mitochondrion . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
信号通路
PI3K/Akt; Protein_Acetylation
功能
caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,function:Molecular chaperone.,function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
