产品名称
eIF4B (phospho-Ser406) Rabbit Polyclonal Antibody
别名
Eukaryotic translation initiation factor 4B (eIF-4B)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1975
Human Swissprot No.
P23588
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P23588/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/75705
Mouse Swissprot No.
Q8BGD9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BGD9
免疫原
Synthesized phosho peptide around human eIF4B (Ser406)
特异性
This antibody detects endogenous levels of Human Mouse Rat eIF4B (phospho-Ser406)
宿主
Polyclonal, Rabbit,IgG
组织表达
Adipose tissue,Brain,Cervix carcinoma,Epithelium,Liver,Lung
细胞定位
cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body,
功能
function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
