产品名称
DNAJC2/MPP11 (phospho-Ser47) Rabbit Polyclonal Antibody
别名
DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1)
基因名称
DNAJC2 MPHOSPH11 MPP11 ZRF1
蛋白名称
DNAJC2/MPP11 (Ser47)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/27000
Human Swissprot No.
Q99543
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99543/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/22791
Mouse Swissprot No.
P54103
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P54103
Rat Gene Link
https://www.uniprot.org/uniprot/116456
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TQ20
免疫原
Synthesized phosho peptide around human DNAJC2 and MPP11 (Ser47)
特异性
This antibody detects endogenous levels of Human Mouse Rat DNAJC2/MPP11 (phospho-Ser47)
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm, cytosol .
功能
PTM:Phosphorylated in M (mitotic) phase.,similarity:Contains 1 J domain.,similarity:Contains 2 SANT domains.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
