产品名称
EP15R Rabbit Polyclonal Antibody
蛋白名称
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UBC2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UBC2/entry
Mouse Swissprot No.
Q60902
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60902
免疫原
Synthesized peptide derived from human protein . at AA range: 350-430
特异性
EP15R Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.,PTM:Phosphorylated on tyrosine residues by EGFR.,similarity:Contains 1 EF-hand domain.,similarity:Contains 3 EH domains.,subcellular location:Localized to plasma membrane coated pits.,subunit:Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).,
组织表达
Brain,Epithelium,Fetal brain,T-cell,Uterus,
细胞定位
Cell membrane ; Peripheral membrane protein . Nucleus . Membrane, coated pit . Localized to plasma membrane coated pits. .
功能
function:Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.,PTM:Phosphorylated on tyrosine residues by EGFR.,similarity:Contains 1 EF-hand domain.,similarity:Contains 3 EH domains.,subcellular location:Localized to plasma membrane coated pits.,subunit:Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
