产品名称
GRPE2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/134266
Human Swissprot No.
Q8TAA5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TAA5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/17714
Mouse Swissprot No.
O88396
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/O88396
免疫原
Synthesized peptide derived from human GRPE2 AA range: 42-92
特异性
This antibody detects endogenous levels of GRPE2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
细胞定位
Mitochondrion matrix .
功能
function:Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.,function:Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.,similarity:Belongs to the grpE family.,subunit:Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, GRPEL1 or GRPEL2, TIMM44, TIMM16/MAGMAS and TIMM14/DNAJC19.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
