产品名称
ACBG1 Rabbit Polyclonal Antibody
基因名称
ACSBG1 BGM KIAA0631 LPD
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23205
Human Swissprot No.
Q96GR2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96GR2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/94180
Mouse Swissprot No.
Q99PU5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99PU5
Rat Gene Link
https://www.uniprot.org/uniprot/171410
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q924N5
免疫原
Synthesized peptide derived from human ACBG1 AA range: 496-546
特异性
This antibody detects endogenous levels of ACBG1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008],
组织表达
Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary.
细胞定位
Cytoplasm . Cytoplasmic vesicle . Microsome . Endoplasmic reticulum . Cell membrane .
功能
catalytic activity:ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.,function:Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.,tissue specificity:Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
