产品名称
CMBL Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/134147
Human Swissprot No.
Q96DG6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96DG6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/69574
Mouse Swissprot No.
Q8R1G2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8R1G2
Rat Gene Link
https://www.uniprot.org/uniprot/310201
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TP52
免疫原
Synthesized peptide derived from human CMBL AA range: 136-186
特异性
This antibody detects endogenous levels of CMBL at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010],
组织表达
Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).
细胞定位
Cytoplasm, cytosol .
功能
similarity:Belongs to the dienelactone hydrolase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
