产品名称
CREB5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9586
Human Swissprot No.
Q02930
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q02930/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/231991
Mouse Swissprot No.
Q8K1L0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K1L0
免疫原
Synthesized peptide derived from human CREB5 AA range: 415-465
特异性
This antibody detects endogenous levels of CREB5 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
功能
function:Binds to the cAMP response element and activates transcription.,similarity:Belongs to the bZIP family.,similarity:Contains 1 bZIP domain.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.