产品名称
JADE3 Rabbit Polyclonal Antibody
基因名称
PHF16 JADE3 KIAA0215
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9767
Human Swissprot No.
Q92613
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92613/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/382207
Mouse Swissprot No.
Q6IE82
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IE82
免疫原
Synthesized peptide derived from human JADE3 AA range: 484-534
特异性
This antibody detects endogenous levels of JADE3 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013],
组织表达
Ubiquitously expressed, with highest levels in placenta and uterus.
细胞定位
histone acetyltransferase complex,
功能
function:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.,induction:By estradiol in estrogen-responsive breast cancer cells.,similarity:Belongs to the JADE family.,similarity:Contains 1 PHD-type zinc finger.,subunit:Component of the HBO1 complex composed at least of ING4 or ING5, MYTS2/HBO1, EAF6, and one of PHF15, PHF16 and PHF17.,tissue specificity:Ubiquitously expressed, with highest levels in placenta and uterus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
