产品名称
QCR1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/7384
Human Swissprot No.
P31930
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P31930/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/22273
Mouse Swissprot No.
Q9CZ13
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CZ13
Rat Gene Link
https://www.uniprot.org/uniprot/301011
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q68FY0
免疫原
Synthesized peptide derived from human QCR1 AA range: 164-214
特异性
This antibody detects endogenous levels of QCR1 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in brain, including substantia nigra, striatum, cortex and cerebellum, and in spinal cord, heart, kidney, liver and muscle.
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .
功能
caution:Does not seem to have a protease activity as it lack the zinc-binding site.,function:This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.,similarity:Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.,subunit:The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.