产品名称
STAR5 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/80765
Human Swissprot No.
Q9NSY2
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NSY2/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/170460
Mouse Swissprot No.
Q9EPQ7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EPQ7
免疫原
Synthesized peptide derived from human STAR5 AA range: 129-179
特异性
This antibody detects endogenous levels of STAR5 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol. Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus. Alternative splicing of this gene produces multiple transcript variants. [provided by RefSeq, Jan 2016],
细胞定位
mitochondrion,cytosol,
功能
function:May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.,similarity:Contains 1 START domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.