产品名称
CSAD Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51380
Human Swissprot No.
Q9Y600
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y600/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/246277
Mouse Swissprot No.
Q9DBE0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9DBE0
Rat Gene Link
https://www.uniprot.org/uniprot/60356
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q64611
免疫原
Synthesized peptide derived from human CSAD AA range: 195-245
特异性
This antibody detects endogenous levels of CSAD at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the group 2 decarboxylase family. A similar protein in rodents plays a role in multiple biological processes as the rate-limiting enzyme in taurine biosynthesis, catalyzing the decarboxylation of cysteinesulfinate to hypotaurine. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
组织表达
Expressed in liver and brain. Also expressed in both astrocytes and neurons, but lower levels are expressed in astrocytes.
功能
catalytic activity:3-sulfino-L-alanine = hypotaurine + CO(2).,cofactor:Pyridoxal phosphate.,pathway:Organosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 2/2.,similarity:Belongs to the group II decarboxylase family.,subunit:Homodimer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
