产品名称
RABEK Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10244
Human Swissprot No.
Q7Z6M1
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z6M1/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/227746
Mouse Swissprot No.
Q8VCH5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VCH5
Rat Gene Link
https://www.uniprot.org/uniprot/296649
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4V8F4
免疫原
Synthesized peptide derived from human RABEK AA range: 227-277
特异性
This antibody detects endogenous levels of RABEK at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
细胞定位
Cytoplasm. Endosome membrane . Interaction with PIKFYVE and subsequent phosphorylation recruits it to the endosomal membrane. .
功能
function:Rab9 effector required for endosome to trans-Golgi network (TGN) transport.,PTM:Phosphorylated on Ser residues most probably by PIP5K3.,similarity:Contains 5 Kelch repeats.,subcellular location:Interaction with PIP5K3 and subsequent phosphorylation recruits it to the endosomal membrane.,subunit:Interacts with PIP5K3. Interacts with RAB9 in its GTP-bound conformation.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
