产品名称
PRD14 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/63978
Human Swissprot No.
Q9GZV8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9GZV8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/383491
Mouse Swissprot No.
E9Q3T6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/E9Q3T6
免疫原
Synthesized peptide derived from human PRD14 AA range: 391-441
特异性
This antibody detects endogenous levels of PRD14 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011],
组织表达
Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level).
功能
function:May be involved in transcriptional regulation.,similarity:Contains 1 SET domain.,similarity:Contains 6 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.