产品名称
MPP2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/4355
Human Swissprot No.
Q14168
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14168/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/50997
Mouse Swissprot No.
Q9WV34
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WV34
免疫原
Synthesized peptide derived from human MPP2 AA range: 439-489
特异性
This antibody detects endogenous levels of MPP2 at Human/Mouse
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton . Membrane . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. .
功能
similarity:Belongs to the MAGUK family.,similarity:Contains 1 guanylate kinase-like domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 L27 domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
