BD-PT7680

PCDB7 Rabbit Polyclonal Antibody

常规抗体

PCDHB7

PCDB7

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

56129

https://www.uniprot.org/uniprot/56129

Q9Y5E2

https://www.uniprot.org/uniprotkb/Q9Y5E2/entry

Synthesized peptide derived from human PCDB7 AA range: 73-123

This antibody detects endogenous levels of PCDB7 at Human

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

87kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. The transcript for this particular family member uses more than one polyadenylation site. [provided by RefSeq, Jul 2008],

Cell membrane ; Single-pass type I membrane protein .

function:Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.,similarity:Contains 6 cadherin domains.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.