产品名称
GPN1 Rabbit Polyclonal Antibody
基因名称
GPN1 MBDIN XAB1 HUSSY-23
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/11321
Human Swissprot No.
Q9HCN4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9HCN4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74254
Mouse Swissprot No.
Q8VCE2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8VCE2
免疫原
Synthesized peptide derived from human GPN1 AA range: 24-74
特异性
This antibody detects endogenous levels of GPN1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
组织表达
Expressed ubiquitously.
细胞定位
Cytoplasm . Nucleus . Shuttles between the nucleus and the cytoplasm. .
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA.,similarity:Belongs to the GPN-loop GTPase family.,subunit:Tightly associated with the RNA polymerase II complex. Interacts with XPA.,tissue specificity:Expressed ubiquitously.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.