产品名称
SUV3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6832
Human Swissprot No.
Q8IYB8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IYB8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/338359
Mouse Swissprot No.
Q80YD1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80YD1
Rat Gene Link
https://www.uniprot.org/uniprot/294385
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5EBA1
免疫原
Synthesized peptide derived from human SUV3 AA range: 443-493
特异性
This antibody detects endogenous levels of SUV3 at Human/Mouse/Rat
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
细胞定位
Nucleus . Mitochondrion matrix . Mitochondrion matrix, mitochondrion nucleoid .
功能
cofactor:Magnesium or manganese.,enzyme regulation:Helicase activity toward DNA substrate is inhibited by micromolar concentrations of 5,6-dichloro-1-(beta-D-ribofuranosyl)benzotriazole (DRBT) and 4,5,6,7-tetrabromobenzotriazole (TBBT). Helicase activity toward RNA substrate is inhibited by elevated concentrations of TBBT. Inhibited by some ring-expanded nucleoside analogs.,function:ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction. May protect cells from apoptosis.,similarity:Belongs to the helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with HBXIP.,tissue specificity:Broadly expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.