产品名称
TRI11 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/81559
Human Swissprot No.
Q96F44
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96F44/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/338364
Mouse Swissprot No.
Q99PQ2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99PQ2
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/B1H278
免疫原
Synthesized peptide derived from human TRI11 AA range: 128-178
特异性
This antibody detects endogenous levels of TRI11 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008],
功能
domain:The coiled-coil domain and the B30.2 domain are both necessary for interaction with humanin.,function:May have E3 ubiquitin ligase activity. May contribute to the regulation of the intracellular level of humanin or humanin-containing proteins through the proteasomal degradation pathway.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Binds cytoplasmic tail of integrin alpha-1. Interacts with the humanin peptide.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
