产品名称
TEKT2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/27285
Human Swissprot No.
Q9UIF3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UIF3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/24084
Mouse Swissprot No.
Q922G7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q922G7
Rat Gene Link
https://www.uniprot.org/uniprot/298532
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6AYM2
免疫原
Synthesized peptide derived from human TEKT2 AA range: 224-274
特异性
This antibody detects endogenous levels of TEKT2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is expressed in the testis and its protein is localized to the flagella of the sperms, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008],
组织表达
Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney.
细胞定位
Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, flagellum axoneme . Cytoplasm, cytoskeleton, microtubule organizing center . Colocalized with CCDC172 at the perinuclear region. .
功能
function:Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.,similarity:Belongs to the tektin family.,subcellular location:In sperm, observed in a discontinuous punctate pattern in the flagellum and in the postacrosomal head region.,tissue specificity:Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
