产品名称
LRRN2 Rabbit Polyclonal Antibody
基因名称
LRRN2 GAC1 LRRN5 UNQ256/PRO293
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10446
Human Swissprot No.
O75325
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75325/entry
免疫原
Synthesized peptide derived from human LRRN2 AA range: 296-346
特异性
This antibody detects endogenous levels of LRRN2 at Human
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],
组织表达
Overamplified in malignant gliomas.
细胞定位
Membrane ; Single-pass type I membrane protein .
功能
similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,tissue specificity:Overamplified in malignant gliomas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
