产品名称
CK092 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Swissprot No.
Q6ZS62
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZS62/entry
免疫原
Synthesized peptide derived from human CK092 AA range: 40-90
特异性
This antibody detects endogenous levels of CK092 at Human
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a transmembrane protein that localizes to granular structures, including crystalloid eosinophilic granules and other granular organelles. This gene, along with an overlapping opposite strand gene, has been implicated as a susceptibility locus for colorectal cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014],
组织表达
Expressed in gastrointestinal and immune tissue, as well as prostate, testis and ovary. Expressed in lamina propria and eosinophils but not in epithelial cells. Expression is greater in benign adjacent tissues than in colon tumors.
细胞定位
Membrane ; Single-pass membrane protein . Co-localizes with crystalloid granules of eosinophils and granular organelles of mast cells, neutrophils, macrophages and dendritic cells.
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
