产品名称
CETN2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1069
Human Swissprot No.
P41208
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P41208/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/26370
Mouse Swissprot No.
Q9R1K9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9R1K9
免疫原
Synthesized peptide derived from human CETN2 AA range: 1-51
特异性
This antibody detects endogenous levels of CETN2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Nucleus envelope . Nucleus, nuclear pore complex . Nucleus .
功能
function:Plays a fundamental role in microtubule-organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CEP110.,miscellaneous:Binds two moles of calcium per mole of protein.,similarity:Belongs to the centrin family.,similarity:Contains 4 EF-hand domains.,subcellular location:Centrosome of S-phase, interphase and mitotic cells.,subunit:Monomer. Interacts with CEP110, SFI1 and with XPC.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
