产品名称
S36A2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/153201
Human Swissprot No.
Q495M3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q495M3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/246049
Mouse Swissprot No.
Q8BHK3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BHK3
Rat Gene Link
https://www.uniprot.org/uniprot/246235
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K415
免疫原
Synthesized peptide derived from human S36A2 AA range: 130-180
特异性
This antibody detects endogenous levels of S36A2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria. [provided by RefSeq, Sep 2010],
组织表达
Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus.
细胞定位
Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane . Recycling endosome membrane .
功能
function:Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine.,similarity:Belongs to the amino acid/polyamine transporter 2 family.,tissue specificity:Abundantly expressed in kidney and muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
