产品名称
ARH40 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55701
Human Swissprot No.
Q8TER5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TER5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/268739
Mouse Swissprot No.
Q3UPH7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UPH7
免疫原
Synthesized peptide derived from human ARH40 AA range: 1261-1311
特异性
This antibody detects endogenous levels of ARH40 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014],
组织表达
Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level).
细胞定位
Cytoplasm . Concentrated in the perinuclear region.
功能
function:May act as a guanine nucleotide exchange factor (GEF).,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,subcellular location:Concentrated in the perinuclear region.,tissue specificity:Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level).,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
