产品名称
ATCAY Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/85300
Human Swissprot No.
Q86WG3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q86WG3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/16467
Mouse Swissprot No.
Q8BHE3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BHE3
Rat Gene Link
https://www.uniprot.org/uniprot/362826
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q1M168
免疫原
Synthesized peptide derived from human ATCAY AA range: 69-119
特异性
This antibody detects endogenous levels of ATCAY at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008],
细胞定位
Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, presynapse . Mitochondrion . Cell projection, growth cone . Cytoplasm .
功能
disease:Defects in ATCAY are the cause of cerebellar ataxia, cayman type (ATCAY) [MIM:601238]. ATCAY is found in a population isolate on Grand Cayman Island and causes a marked psychomotor retardation and prominent nonprogressive cerebellar dysfunction including nystagmus, intention tremor, dysarthria, and wide-based ataxic gait. Hypotonia is present from early childhood.,domain:The CRAL-TRIO domain is known to bind small hydrophobic molecules.,similarity:Contains 1 CRAL-TRIO domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
