产品名称
AAAT Rabbit Polyclonal Antibody
基因名称
SLC1A5 ASCT2 M7V1 RDR RDRC
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6510
Human Swissprot No.
Q15758
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q15758/entry
Mouse Swissprot No.
P51912
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P51912
免疫原
Synthesized peptide derived from human AAAT AA range: 345-395
特异性
This antibody detects endogenous levels of AAAT at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011],
组织表达
Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
细胞定位
Cell membrane ; Multi-pass membrane protein . Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
功能
alternative products:A number of isoforms are produced by alternative initiation. Isoforms start at multiple alternative CUG and GUG codons,function:Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Act as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
