产品名称
IDI1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3422
Human Swissprot No.
Q13907
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13907/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/319554
Mouse Swissprot No.
P58044
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P58044
Rat Gene Link
https://www.uniprot.org/uniprot/89784
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/O35760
免疫原
Synthesized peptide derived from human IDI1 AA range: 103-153
特异性
This antibody detects endogenous levels of IDI1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008],
功能
catalytic activity:Isopentenyl diphosphate = dimethylallyl diphosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).,pathway:Isoprenoid biosynthesis; dimethylallyl-PP biosynthesis; dimethylallyl-PP from isopentenyl-PP: step 1/1.,similarity:Belongs to the IPP isomerase type 1 family.,subunit:Monomer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
