产品名称
NUDT9 Rabbit Polyclonal Antibody
基因名称
NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/53343
Human Swissprot No.
Q9BW91
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BW91/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/74167
Mouse Swissprot No.
Q8BVU5
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BVU5
Rat Gene Link
https://www.uniprot.org/uniprot/305149
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XIG0
免疫原
Synthesized peptide derived from human NUDT9 AA range: 107-157
特异性
This antibody detects endogenous levels of NUDT9 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
组织表达
Ubiquitously expressed but isoform 1 is the most predominant isoform.
细胞定位
[Isoform 1]: Mitochondrion.
功能
catalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,cofactor:Magnesium.,cofactor:Manganese.,function:Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.,induction:Isoform 1 is inhibited by fluoride and N-acetyl-p-benzoquinoneimine.,similarity:Belongs to the Nudix hydrolase family. NudF subfamily.,subunit:Monomer. Interacts with C17orf25.,tissue specificity:Ubiquitously expressed but isoform 1 is the most predominant isoform.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
