产品名称
MAST1 Rabbit Polyclonal Antibody
蛋白名称
Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9Y2H9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Y2H9/entry
Mouse Swissprot No.
Q9R1L5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R1L5
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q810W7
免疫原
Synthesized peptide derived from human protein . at AA range: 300-380
特异性
MAST1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Colocalizes with syntrophins at the cell membrane.,subunit:Part of a low affinity complex that associates with, but is distinct from, the post-synaptic density. Interacts with SNTB2.,
组织表达
Expressed in fetal brain.
细胞定位
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Also localized in the soma of neurons. Observed as punctate clusters in the processes of interneurons and along the cell body periphery. Colocalizes with syntrophins at the cell membrane. .
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Colocalizes with syntrophins at the cell membrane.,subunit:Part of a low affinity complex that associates with, but is distinct from, the post-synaptic density. Interacts with SNTB2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
